What is RALLEE®?

RALLEE® is MoxxiTech’s genetic testing platform, comprised of whole genome sequencing and our proprietary analysis software, and optimized to identify unique and complex genetic mutations from single nucleotide polymorphisms (SNPs) to large DNA deletions and insertions that may be responsible for genetic diseases. 

RALLEE® Certified diagnostic genetic testing panels are currently available for cattle, dogs, cats, and horses. Our vast offerings have been divided into convenient panels based on overlapping diseases symptoms to aid in the diagnosis of rare and complex genetic disorders. Custom whole genome analysis is also available when conventional genetic testing panels are inconclusive, when a novel or unique genetic mutation is expected, or for those who would like an advanced screening of their animal’s genome prior to breeding.

 Learn more about genetic testing here.

 

What is the testing process?

Ordering:

  1. Click Here to register for an account online. Once registered, you may place an order directly on our website for the tests you would like performed. If you would like to place an order without registering, please call our laboratory directly at 1-833-741-1741.
  2. Once registered, you may place an order directly on our website for the tests you would like performed. Click here to view RALLEE Genetic Tests.

Please note: we request that all samples be drawn by a veterinarian for your safety and the safety of your animals. 

However, samples provided for Custom Diagnostic Genetic Testing must be drawn by a veterinarian and must be accompanied by a completed RALLEE Requisition Form, including all relevant medical charts.

Sample Collection:

Whole genome sequencing is an extremely sensitive technique that requires high quality DNA free of any potential contaminants. Thus, all RALLEE® Certified diagnostic test panels require whole blood samples as the DNA source.

    • A minimum of 3 mLs of whole blood is required. 
    • Blood may be collected in EDTA (purple top) tubes or in MoxxiTech’s DNA preservation tubes (provided in our free collection kit).
    • In certain cases other sample types (such as semen) may be used in place of blood, but please contact us to confirm prior to shipment.
    • Post-mortem genetic testing- at times genetic testing of animals post-mortem may be important to help a veterinarian confirm a cause of death or to help a breeder make appropriate choices to their breeding program. In these instances whole blood samples are still preferred but samples from other sources may be accepted. Please contact our laboratory prior to shipping any post-mortem specimens to confirm the best specimen for genetic testing in your unique case.

Sample Labeling:

All samples must be labeled to be accepted by our laboratory. Please follow our labeling instructions to prevent any testing delays. All samples must be labeled with:

    • Patient’s name or unique identification number
    • Owner’s name
    • Date of sample collection

Sample Packaging and Shipping: 

    • Samples should be packaged following the government and FedEx’s Packaging Guidelines for Clinical Samples. Multiple samples may be included in the same FedEx Clinical Pak as long as all labeling guidelines are strictly followed. 
    • Whole blood samples in EDTA (purple top) tubes should be shipped overnight, preferably the same day as sample collection.
    • Samples in MoxxiTech’s provided DNA preservation tubes may be kept at room temperature until shipped. 
    • If shipping the same day as collection is not possible, please keep the sample refrigerated and ship within 48 hours of collection. DO NOT FREEZE ANY SAMPLES AT ANY TIME. Freezing samples will lower DNA quality and will require a new sample to be collected.
    • Please include cold packs with all samples during times of warm weather.
    • Include a completed copy of the requisition form with the sample.
    • Shipments are accepted Monday-Friday; please do not send shipments for Saturday delivery or on FedEx holidays to prevent sample degradation. We suggest shipping from your location Monday-Thursday to ensure samples are received on time.

Sample Processing and Sequencing:

Once received in our laboratory, our scientists carefully extract and process the DNA for whole genome sequencing. After processing, the purified DNA undergoes multiple quality checks to confirm its suitability for whole genome sequencing. If the DNA passes all quality checks our scientists will begin the whole genome sequencing process. Sequencing, on average, takes 72-96 hours for completion, after which the sequencing results are submitted to our bioinformatics department for analysis. 

Sequencing Analysis and Reporting:

Our dedicated bioinformatics department carefully analyzes the sequencing results using our proprietary analysis software. Analysis can take up to two weeks, depending on the number of samples submitted and the chosen test panel. Custom analysis may take 6-8 weeks to finalize our analysis. Once our analysis is complete, a report will be generated and sent by email to the submitting veterinarian and to the client listed on the order form, if selected. 

Can I add custom analysis to my order after sequencing is finished? 

Yes! Custom sequencing analysis can be added to any order any time after the initial sequencing. Please Contact Us directly for any changes to your order. 

RALLEE® Certified Genetic Panels and Expert Analysis  

Find out more about our unique diagnostic tests through our links below:

Find a list of the genes and diseases included in each panel in the tabs below

For Symptoms Involving: Development, Hearing, Musculoskeletal System, Nervous System, Vision

Number of Alleles Tested: 114

  

Condition

Gene(s)

Chondrodysplasia 1-7

ACAN, EVC2, FGFR3

Pulmonary Hypoplasia and Anasarca Syndrome (PHA)

ADAMTS3

Contractural Arachnodactyly (Fawn calf syndrome)

ADAMTSL3

Arthrogryposis Multiplex Congenita (Curly Calf Syndrome) 1-3

AGRN, CHRNB1, PIGH

Tibial Hemimelia 1, 2

ALX4

Cholesterol Deficiency (CD)

APOB

Citrullinemia

ASS1

Congenital Muscular Dystonia 1 (CMD1)

ATP2A1

Congenital Pseudomyotonia 1, 2 (PMT 1, 2)

ATP2A1

Maple Syrup Urine Disease 1, 2 (MSUD 1, 2)

BCKDHA

Seckel-like Syndrome (SHGC)

CEP250

Neurocristopathy

CHD7

Myasthenic Syndrome

CHRNE

Osteopetrosis with gingival hamartomas 1, 2

CLCN7, SLC4A2

Renal Tubular Dysplasia (RTD1, 2) 1, 2

CLDN16

Neuronal Ceroid Lipofuscinosis 5 (NCL5)

CLN5

Osteogenesis Imperfecta Type II 1, 2

COL1A1

Achondrogenesis Type II 1-7 (Bulldog calf syndrome 1-7)

COL2A1

Morgagnian Cataract

CPAMD8

Marfan Syndrome (MFS) 1, 2

FBN1

Facial Dysplasia Syndrome

FGFR2

Trimethylaminuria

FMO3

Generalized Glycogenosis Type II 1-3

GAA

Dwarfism 1-4

GH1, GON4L, PRKG2, RNF11

Myoclonus

GLRA1

Diaphragmatic Muscle Myopathy (HMDM)

HSPA1A

Perinatal Weak Calf Syndrome

IARS

Immunodeficiency

IL17RA

Leukocyte Adhesion Deficiency

ITGB2

Lethal Multi-Organ Developmental Dysplasia

KDM2B

Spinal Muscular Atrophy

KDSR

Hypomyelinogenesis

KIF1C

Hypotrichosis 2

KRT71

Congenital Muscular Dystonia 2 (CMD2)

SLC6A5

Syndactyly 1-5

LRP4

Alpha-Mannosidosis 1, 2

MAN2B1

Beta-Mannosidosis 1

MANBA

Degenerative Axonopathy

MFN2

Microphthalmia

MITF

Dominant White with Bilateral Deafness 1, 2

MITF

Xanthinuria Type II 1, 2

MOCOS

Arachnomelia 1, 2

MOCS1, SUOX

Crooked Tail Syndrome 1, 2

MRC2

Double Muscling 1-9

MSTN

Arthrogryposis Type 1B

MYBPC1

Mucopolysaccharidosis IIIB

NAGLU

Polymelia and Neural Tube Defects

NHLRC2

Cataracts

NID1

Niemann-Pick Disease Type 1

NPC1

Abortion 11, 12

OBFC1, PFAS

Dilated Cardiomyopathy

OPA3

Zinc Deficiency-Like Syndrome

PLD4

Progressive Degenerative Myeloencephalopathy

PNPLA8

Cardiomyopathy

PPP1R13L

Bovine Spongiform Encephalopathy

PRNP

Glycogen Storage Disease V

PYGM

Interdigital Hyperplasia

ROR2

Retinitis Pigmentosa

RP1

Tetradysmelia

RSPO2

Fanconi-Bickel Syndrome

SLC2A2

Turning Calves Syndrome

SLC25A46

Complex Vertebral Malformation 1, 2

SLC35A3

Spinal Dysmyelination

SPAST

Vertebral and Spinal Dysplasia

T

PIRM Syndrome

UBE3B

Multiple Ocular Defects (MOD)

WFDC1

Polled and Multisystemic Syndrome (PMS) 1, 2

ZEB2

Frontonasal Dysplasia 1

ZIC2

 

For Symptoms Involving: Blood, Gastrointestinal Tract Heart, Immune System, Kidneys, Liver, Lungs

Number of Alleles Tested: 29

  

Condition

Gene(s)

Cholesterol Deficiency (CD)

APOB

Congenital Muscular Dystonia 1 (CMD1)

ATP2A1

Neurocristopathy

CHD7

Renal Tubular Dysplasia (RTD1,2) 1, 2

CLDN16

Chondrodysplasia 3-5

EVC2

Hemophilia A 1, 2

F8

Factor XI Deficiency 1, 2

F11

Brachyspina Syndrome (BS)

FANCI

Marfan Syndrome (MFS) 1, 2

FBN1

Protoporphyria

FECH

Immunodeficiency

IL17RA

Leukocyte Adhesion Deficiency

ITGB2

Lethal Multi-Organ Developmental Dysplasia

KDM2B

Chediak-Higashi Syndrome

LYST

Niemann-Pick Disease Type I

NPC1

Dilated Cardiomyopathy

OPA3

Zinc Deficiency-Like Syndrome

PLD4

Cardiomyopathy

PPP1R13L

Thrombopathia

RASGRP2

Dwarfism 4

RNF11

Fanconi-Bickel Syndrome

SLC2A2

Spherocytosis

SLC4A1

Acrodermatitis Enteropathica

SLC39A4

For Symptoms Involving; Dental, Dermal, Endocrine System, Hair, Metabolism, Milk Production, Reproduction

Number of Alleles Tested: 79

  

Condition

Gene(s)

Ichthyosis Fetalis (IF) 1-3

ABCA12

Chondrodysplasia 1-3

ACAN

Dermatosparaxis

ADAMTS2

Pulmonary Hypoplasia and Anasarca Syndrome (PHA)

ADAMTS3

Tibial Hemimelia 1, 2

ALX4

Abortion 1-24

ANXA10, APAF1, CAD, CENPU, CWC15, EXOSC4, GART, MED22, MIMT1, MYH6, OBFC1, PFASRABGGTB, RNASEH2B, RNF20, RPIA, SDE2, SHBG, SLC37A2, SMC2, SUGT1, TFB1M, TTF1, TUBD1

Tail Stump Sperm Defect

ARMC3

Athenospermia

CCDC189

Epidermolysis Bullosa 1-5

COL7A1, ITGB4, KRT5, LAMA3, LAMC2

Tricho-dento-osseous-like syndrome

DLX3

Anhidrotic Ectodermal Dysplasia 1-7 (XLHED1-7)

EDA, EDAR

Ehlers-Danlos Syndrome Variant 1

EPYC

Factor XI Deficiency 1, 2

F11

Brachyspina Syndrome (BS)

FANCI

Trimethylaminuria

FMO3

Dwarfism

GH1

Hypotrichosis 1, 2

HEPHL1, KRT71

Immunodeficiency

IL17RA

Lethal Multi-Organ Developmental Dysplasia

KDM2B

Spinal Muscular Atrophy

KDSR

Gonadal Hypoplasia (Cs^29)

KIT

Dominant White with Bilateral Deafness 1, 2

MITF

Zinc Deficiency-Like Syndrome

PLD4

Hydrallantois

SLC12A1

Complex Vertebral Malformation 1, 2

SLC35A3

Acrodermatitis Enteropathica

SLC39A4

Oculocutaneous Albinism Type IV 1, 2

SLC45A2

Arachnomelia 2

SUOX

Goiter

TG

Male Subfertility

TMEM95

Streaked Hairlessness

TSR2

Scurs Type II

TWIST1

Oculocutaneous Albinism Type I

TYR

Deficiency of Uridine Monophosphate Synthase (DUMPS)

UMPS

Polled and Multisystemic Syndrome (PMS) 1, 2

ZEB2

 

Includes all diseases tested in Panels 1-3 and custom sequencing and analysis to identify unique DNA mutations. 

Requires veterinary submission of medical records to guide our scientists in the custom analysis.

For symptoms involving: Drug Metabolism, Nervous System, Hearing, Vision

Number of Alleles Tested: 174

  

Condition

Gene(s)

AC-3933 Poor Metabolizer 1

CYP1A2

Achromatopsia 1-4

CNGA3, CNGB3

Acral Mutilation Syndrome

GDNF

Alexander Disease

GFAP

Beta Mannosidosis 1, 2

MANBA

Bilateral Deafness and Vestibular Dysfunction

MYO7A

Cerebellar Ataxia 1,2

RAB24, KCNIP4

Cerebellar Cortical Degeneration

SNX14

Cerebellar Hypoplasia

VLDLR

Collie Eye Anomaly

NHEJ1

Cone Rod Dystrophy, Age of Onset Modifier

MAP9

Cone-Rod Dystrophy 1-4

NPHP4, IQCB1, RPGRIP1

Congenital Eye Malformations

SIX6

Congenital Myasthenic Syndrome 1-5

CHAT, CHRNE, COLQ

Copper Toxicosis

COMMD1

Deafness, Unilateral and Vestibular Dysfunction

PTPRQ

Degenerative Myelopathy

SOD1

Demyelinating Peripheral Neuropathy

SBF2

Dermoid Sinus

FGF3

Early Onset Cataracts 1, 2

HSF4

Early Retinal Degeneration

STK38L

Epileptic Drug Resistance

ABCB1

Episodic Falling Syndrome

BCAN

Fetal Onset Neuroaxonal Dystrophy

MFN2

Fucosidosis Alpha

FUCA1

Gangliosidosis 1-3

GLB1

Generalized Myoclonic Epilepsy

DIRAS1

Generalized Progressive Retinal Atrophy 1, 2

ADAM9, CCDC66

Globoid Cell Leukodystrophy 1, 2

GALC

GM2 Gangliosidosis Type I

HEXA

GM2 Gangliosidosis Type II 1, 2

HEXB

Hepatic Copper Toxicosis

ATP7B

Hyperekplexia 1, 2

SLC6A5

Hypomyelination of Central Nervous System

FNIP2

Hypophosphatasia

ALPL

Ivermectin Sensitivity 1, 2

ABCB1

L-2-Hydroxyglutaric Aciduria 1, 2

L2HGDH

Lagotto Storage Disease

ATG4D

Laryngeal Paralysis Risk Factor

RAPGEF6

Leber Congenital Amaurosis

RPE65

Leukodystrophy 1, 2

CYTB, TSEN54

Leukoencephalopathy 1, 2

NAPEPLD

Macular Corneal Dystrophy

LOC489707

Merle/Cryptic Merle

PMEL

Micropthalmia

RBP4

Mucopolysaccharidosis Type I

IDUA

Mucopolysaccharidosis Type IIIA 1, 2

SGSH

Mucopolysaccharidosis Type IIIB 1, 2

NAGLU

Multifocal Retinopathy I 1, 2

BEST1

Multifocal Retinopathy II

BEST1

Multifocal Retinopathy III 1, 2

BEST1

Myoclonus Epilepsy of Lafora

NHLRC1

Myotubular Myopathy 1, 2

MTM1

Narcolepsy 1-3

HCRTR2

Necrotising Encephalopathy

SLC19A3

Neonatal Cerebellar Ataxia

GRM1

Neonatal Encephalopathy With Seizures

ATF2

Neuroaxonal Dystrophy 1-3

PLA2G6, TECPR2, VPS11

Neuronal Ceroid Lipofuscinosis 1

PPT1

Neuronal Ceroid Lipofuscinosis 2

TPP1

Neuronal Ceroid Lipofuscinosis 3

PPT1

Neuronal Ceroid Lipofuscinosis 4A 1

ARSG

Neuronal Ceroid Lipofuscinosis 5 1, 2

CLN5

Neuronal Ceroid Lipofuscinosis 6

CLN6

Neuronal Ceroid Lipofuscinosis 7

MFSD8

Neuronal Ceroid Lipofuscinosis 8 1-4

CLN8

Neuronal Ceroid Lipofuscinosis 10

CTSD

Neuronal Ceroid Lipofuscinosis 12 1, 2

ATP13A2

Oculocutaneous Albinism

OCA2

Oculocutaneous Albinism Type IV 1-3

SLC45A2

Oculoskeletal Dysplasia I 1, 2

COL9A3

Oculoskeletal Dysplasia II

COL9A2

Osteochondromatosis

EXT2

Paroxysmal Dyskinesia

PIGN

Periodic Fever Syndrome

MTBP

Photoreceptor Dysplasia

PPT1

Polyneuropathy 1-6

NDRG1, RAB3GAP1, ARHGEF10, GJA9

Pompe Disease

GAA

Primary Glaucoma 1, 2

ADAMTS10

Primary Lens Luxation

ADAMTS17

Primary Open Angle Glaucoma 1-3

ADAMTS17

Primary Open Angle Glaucoma and/or Primary Lens Luxation

ADAMTS17

Progressive Early Onset Cerebellar Ataxia

SEL1L

Progressive Retinal Atrophy 1-10

BBS4, HIVEP3, CNGA1, CNGB1, MERTK, NECAP1, SAG1, SLC4A3, TTC8, RHO

Progressive Retinal Atrophy Type 2

C17H2orf71

Progressive Retinal Atrophy X-Linked Type 1, 1-3

RPGR

Progressive Retinal Atrophy X-Linked Type 2

RPGR

Progressive Rod-Cone Degeneration (PRCD-PRA)

PRCD

Protection Against Liver Copper Accumulation

ATP7A

Refractory Idiopathic Epilepsy

ABCB1

Remitting Focal Epilepsy

LGI2

Rod-Cone Dysplasia Type 1, 1-4

PDE6B

Rod-Cone Dysplasia Type 3

PDE6A

Selective Cobalamin Malabsorption 1-3

CUBN

Sensory Ataxic Neuropathy

tRNA-TYR

Sensory Neuropathy

FAM134B

Spinal Dyraphism

NKX2-8

Spinocerebellar Ataxia 1-7

SCN8A, KCNJ10, SPTBN2, CAPN1, ITPR1

Spongy Degeneration with Cerebellar Ataxia 1, 2

ATP1B2

Stargardt Disease

ABCA4

Tremor

PLP

For symptoms involving: Development, Musculoskeletal System, Reproduction, Skin and Hair, Teeth and Oral Cavity

Number of Alleles Tested: 160

  

Condition

Gene(s)

Abortion

BTBD17

Alexander Disease

GFAP

Amelogenesis Imperfecta 1-3

ACP4, ENAM

Bernard-Soulier Syndrome Type C

GP9

Beta Mannosidosis 1, 2

MANBA

Centronuclear Myopathy 1, 2

BIN1, HACD1

CHILD-like Syndrome

NSDHL

Chondrodysplasia

ITGA10

Chondrodystrophy (HT1)

CFA 12

Ciliary Dyskinesia 1, 2

CCDC39, NME5

Cleft Lip and Palate

ADAMTS20

Cleft Palate

DLX6

Coat Color Dilution (d^1, d^2)

MLPH

Congenital Ichthyosis

NIPAL4

Congenital Keratoconjunctivitis Sicca and Ichthyosiform Dermatosis

FAM83H

Congenital Myasthenic Syndrome 1-4

CHAT, CHRNE, COLQ

Craniomandibular Osteopathy 1-4

SLC37A2, COL1A1, SLC35D1

Cushing’s Syndrome 1-6

GNAS

Cyclic Neutropenia

AP3B1

Decreased Fecundity

GDF9

Dental Hypomineralization

FAM20C

Dermatosparaxis

ADAMTS2

Dermoid Sinus

FGF3

Disorder of Sexual Development

HSD17B3

Disproportionate Dwarfism

COL11A2

Dystrophic Epidermolysis Bullosa 1, 2

COL7A1

Ectodermal Dysplasia, 1-2

FOXI3, PKP1

Ehlers-Danlos Syndrome 1-4

COL5A1, TNXB

Epidermolysis Bullosa

PLEC

Epidermolytic Hyperkeratosis

KRT10

Episodic Falling Syndrome

BCAN

Exercise Induced Collapse

DNM1

Exercise Induced Metabolic Myopathy

ACADVL

Exfoliative Cutaneous Lupus Erythematosus (ECLE)

UNC93B1

Fanconi Syndrome

FAN1

Fucosidosis Alpha

FUCA1

Gangliosidosis 1-3

GLB1

Globoid Cell Leukodystrophy 1, 2

GALC

Glycogen Storage Disease IIIa 1

AGL

Glycogen Storage Disease VII 1, 2

PFKM

Hereditary Methemoglobinemia 1, 2

CYB5R3

Hyperkeratosis

FAM83G

Hypomyelination of Central Nervous System

FNIP2

Hypophosphatasia

ALPL

Hypothyroidism 1-4

TPO

Hypotrichosis 1, 2

SGK3

Ichthyosis 1-4

ASPRV1, PNPLA1, SLC27A4, TGM1

Intestinal Cobalamin Malabsorption

AMN

Junctional Epidermolysis Bullosa

LAMA3

Lethal Acrodermatitis

MKLN1

Leukodystrophy

CYTB

Ligneous Membranitis

PLG

Limb Girdle Muscular Dystrophy Type 2F

SGCD

Malignant Hyperthermia

RYR1

Merle (Mc, Mc+, Ma, Ma+, M, Mh)

PMEL

Mucopolysaccharidosis Type I 1

IDUA

Mucopolysaccharidosis Type VI 1, 2

ARSB

Mucopolysaccharidosis Type VII 1, 2

GUSB

Muscular Dystrophy 1-8

COL6A1, DMD

Muscular Hypertrophy

MSTN

Musladin Lueke Syndrome

ADAMTSL2

Myotonia 1-3

CLCN1

Nasal Parakeratosis 1, 2

SUV39H2

Nemaline Myopathy

NEB

Oculocutaneous Albinism

OCA2

Oculocutaneous Albinism Type IV 1-3

SLC45A2

Oculoskeletal Dysplasia 1, 2

COL9A2, COL9A3

Osteochondrodysplasia

SLC13A1

Osteochondromatosis

EXT2

Osteogenesis Imperfecta 1-5

COL1A1, COL1A2, SERPINH1

Palmoplantar Keratoderma

KRT16

Paroxysmal Dyskinesia

PIGN

Periodic Fever Syndrome 1, 2

HAS2, MTBP

Persistant Mullerian Duct Syndrome

AMHR2

Pituitary Dwarfism

LHX3

Polyneuropathy 1-6

NDRG1, RAB3GAP1, ARHGEF10, GJA9

Pompe Disease

GAA

Pyruvate Dehydrogenase Deficiency

PDP1

Pyruvate Kinase Deficiency of Erythrocyte 1-6

PKLR

Screw Tail

DVL2

Selective Cobalamin Malabsorption 1-3

CUBN

Spinal Dyraphism

NKX2-8

Spinocerebellar Ataxia 6

CAPN1

Spondylocostal Dysostosis

HES7

Tail Length (TBXT)

T (TBXT)

Van den Ende-Gupta Syndrome

SCARF2

Vitamin D Deficiency Rickets Type II

VDR

X-linked Hypohidrotic Ectodermal Dysplasia 1, 2

EDA

For symptoms involving: Blood, Cancer, Endocrine System, Gastrointestinal Tract, Heart, Immune System, Kidneys, Liver, Metabolism, Respiratory System

Number of Alleles Tested: 135

  

Condition

Gene(s)

Acute Respiratory Distress Syndrome

ANLN

Bernard-Soulier Syndrome Type C

GP9

C3 Deficiency

C3

Cardiomyopathy

YARS2

Ciliary Dyskinesia 1, 2

CCDC39, NME5

Colorectal Hamartomatous Polyposis and Ganglioneuromatosis

PTEN

Congenital Dyshormonogenic Hypothyroidism

SLC5A5

Copper Toxicosis

COMMD1

Cushing’s Syndrome 1-6

GNAS

Cyclic Neutropenia

AP3B1

Cystinuria Type IA

SLC3A1

Cystinuria Type IIA 1, 2

SLC3A1

Cystinuria Type IIB

SLC7A9

Demyelinating Peripheral Neuropathy

SBF2

Diffuse Cystic Renal Dysplasia and Hepatic Fibrosis

INPP5E

Dilated Cardiomyopathy

PLN

Elliptocytosis

SPTB

Exercise Induced Metabolic Myopathy

ACADVL

Factor VII Deficiency

F7

Factor XI Deficiency

F11

Fanconi Syndrome

FAN1

Fatal Neonatal Interstitial Lung Disease

LAMP3

Gallbladder Mucoceles

ABCB4

Gastrointestinal Stromal Tumors 1-6

KIT

Glycogen Storage Disease Ia

G6PC

Glycogen Storage Disease IIIa

AGL

Glycogen Storage Disease VII 1, 2

PFKM

Hemophilia A 1-5

F8

Hemophilia B 1-7

F9

Hepatic Copper Toxicosis

ATP7B

Hereditary Nephritis

COL4A5

Hereditary Methemoglobinemia 1, 2

CYB5R3

Hereditary Nephropathy 1-3

COL4A4, COL4A5

Hypocatalasia

CAT

Hypothyroidism 1-4

TPO

Inflammatory Pulmonary Disease

AKNA

Intestinal Cobalamin Malabsorption

AMN

Invasive Transitional Cell Carcinoma

BRAF

Laryngeal Paralysis Risk Factor

RAPGEF6

Lethal Acrodermatitis

MKLN1

Leukocyte Adhesion Deficiency

FERMT3

Leukocyte Adhesion Deficiency Type I

ITGB2

Ligneous Membranitis

PLG

Lundehund Syndrome

LEPREL1

Malignant Hyperthermia

RYR1

May-Hegglin Anomaly

MYH9

Mucopolysaccharidosis Type I

IDUA

Mucopolysaccharidosis Type VI 1, 2

ARSB

Myeloperoxidase Deficiency

MPO

Myotubular Myopathy 1, 2

MTM1

Obesity and Food Motivation

POMC

Oculocutaneous Albinism Type IV 1-3

SLC45A2

Pancreatitis Variant 1-3

SPINK1

Periodic Fever Syndrome 1,2

HAS2, MTBP

Pituitary Dwarfism

LHX3

Polycystic Kidney Disease

PKD1

Pompe Disease

GAA

Postoperative Hemorrhage

P2RY12

Prekallikrein Deficiency

KLKB1

Primary Hyperoxaluria

AGXT

Primary Polycythemia 1

JAK2

Protection Against Liver Copper Accumulation

ATP7A

Pyruvate Dehydrogenase Deficiency

PDP1

Pyruvate Kinase Deficiency of Erythrocyte 1-6

PKLR

Renal Cystadenocarcinoma

FLCN

Scott Syndrome

ANO6

Selective Cobalamin Malabsorption 1-3

CUBN

Severe Combined Immunodeficiency Disease 1,2

PRKDC, RAG1

Squamous Cell Carcinoma

KITLG

Thrombasthenia 1-3

ITGA2B

Thrombocytopenia 1, 2

TUBB1

Thrombopathia 1-3

RASGRP1

Trapped Neutrophil Syndrome

VPS13B

Upper Airway Syndrome

ADAMTS3

Urolithiasis

SLC2A9

Vitamin D Deficiency Rickets Type II

VDR

Von Willebrand Disease Type I

VWF

Von Willebrand Disease Type II 1, 2

VWF

Von Willebrand Disease Type III 1-3

VWF

X-linked Severe Combined Immunodeficiency 1, 2

IL2RG

Includes all diseases tested in Panels 1-3 and custom sequencing and analysis to identify unique DNA mutations. 

Requires veterinary submission of medical records to guide our scientists in the custom analysis.

For symptoms involving: Development, Hair, Hooves, and Skin, Musculoskeletal System

Number of Alleles Tested: 19

  

Condition

Gene(s)

Dwarfism (D1-4)

ACAN

Dwarfism with Joint Laxity

B4GALT7

Congenital Myotonia

CLCN1

Skeletal Muscle Glycogenesis (PSSM)

GYS1

Malignant Hyperthermia

RYR1

Hyperkalemic Periodic Paralysis (HYPP)

SCN4A

Epidermolysis Bullosa Junctionalis

LAMA3

Hereditary Junctional Mechanobullous Disease

LAMC2

Hereditary Equine Regional Dermal Asthenia (HERDA)

PPIB

Hoof Wall Separation Disease (HWSD)

SERPINB11

Naked Foal Syndrome (NFS)

ST14

Glycogen Storage Disease IV (GBED)

GBE1

Occipitoatlantoaxial Malformation (OAAM)

HOXD3

Skeletal Atavism

SHOX

Incontinentia Pigmenti 1

IKBKG

Warmblood Fragile Foal Syndrome Type (WFFS)

PLOD1

For symptoms involving: Blood, Cancer, Endocrine System, Gastrointestinal Tract, Heart, Immune System, Liver, Nervous System, Reproduction, Vision

Number of Alleles Tested: 19

  

Condition

Gene(s)

Androgen Insensitivity 1-5

AR

Hydrocephalus

B3GALNT2

Limbal Squamous Cell Carcinoma

DDB2

Melanoma Susceptibility

ASIP

Lethal White Foal Syndrome

EDNRB

Glanzmann Thrombasthenia 1, 2

ITGA2B

Cerebellar Abiotrophy

TOE1

Lavender Foal Syndrome

MYO5A

Immune Mediated Myositis (IMM) Susceptibility

MYH1

Multiple Congenital Ocular Anomalies

PMEL

Severe Combined Immunodeficiency

PRKDC

Foal Immunodeficiency Syndrome

SLC5A3

Congenital Stationary Night Blindness (CSNB)

TRPM1

Disorder of Sexual Development (Sex Reversal)

AKR1C

Glycogen Storage Disease IV (GBED)

GBE1

Occipitoatlantoaxial Malformation (OAAM)

HOXD3

Skeletal Atavism

SHOX

Incontinentia Pigmenti

IKBKG

Warmblood Fragile Foal Syndrome Type (WFFS)

PLOD1

Includes all diseases tested in Panels 1-2 and custom sequencing and analysis to identify unique DNA mutations. 

Requires veterinary submission of medical records to guide our scientists in the custom analysis. 

For symptoms involving: Hearing, Nervous System, Vision

Number of Alleles Tested: 30

  

Condition

Gene(s)

Alpha Mannosidosis

MAN2B1

Brachycephaly and Craniofacial Defects

ALX1

Congenital Glaucoma

LTBP2

Dihydropyrimidinase (DHP)

CPYS

Erythrocyte Pyruvate Kinase Deficiency (PK Deficiency)

PKLR

Glycogen Storage Disease Type IV (GSD IV)

GBE

GM1 Gangliosidosis 1-5

GLB1, GM2A, HEXB

Hemophilia B 1, 2

F9

Hypokalemic Periodic Paralysis

WNK4

Leber Congenital Amaurosis (or Retinal Pigment Epithelial Dystrophy)

AIPL

Mucolipidosis II

GNPTAB

Mucopolysaccharidosis VII 1, 2

GUSB

Neuronal Ceroid Lipofuscinosis Type 7 (CLN7)

MFSD8

Niemann-Pick Disease Type C1 (NPC1) 1, 2

NPC1

Niemann-Pick Disease Type C2 (NPC2)

NPC2

Retinal Degeneration II

CEP290

Rickets Type 1B

CYP2R1

Rickets Type I 1, 2

CYP27B1, CYP27B2

Rod-Cone Dysplasia

CRX

Spasticity (Congenital Myasthenic Syndrome, CMS)

COLQ

Spinal Muscular Atrophy

LIX1

For symptoms involving: Development, Musculoskeletal System, Skin and Hair

Number of Alleles Tested: 45

  

Condition

Gene(s)

Acute Intermittent Porphyria (AIP) 1-6

HMBS

Alpha Mannosidosis

MAN2B1

Brachycephaly and Craniofacial Defects

ALX1

Chediak-Higashi Syndrome

LYST

Congenital Hypothyroidism

TPO

Dihydropyrimidinase (DHP)

CPYS

Ehlers-Danlos Syndrome, Classic Type I (EDS)

COL5A1

Erythrocyte Pyruvate Kinase Deficiency (PK Deficiency)

PKLR

Erythropoietic Porphyria

UROS

Fibrodysplasia Ossificans

ACVR1

Glycogen Storage Disease Type IV (GSD IV)

GBE

GM1 Gangliosidosis 1-5

GLB1, GM2A, HEXB

Hairless with shortened lifespan

FOXN1

Hemophilia B 1, 2

F9

Hyperlipoproteinaemia

LPL

Hypokalemic Periodic Paralysis

WNK4

Inflammatory Linear Verrucous Epidermal Nevus (ILVEN)

NSDHL

Mucolipidosis Type II

GNPTAB

Mucopolysaccharidosis Type I

IDUA

Mucopolysaccharidosis Type VI

ARSB

Mucopolysaccharidosis VII 1, 2

GUSB

Myotonia Congenita

CLCN1

Neuronal Ceroid Lipofuscinosis Type 7 (CLN7)

MFSD8

Niemann-Pick Disease Type C1 (NPC1) 1, 2

NPC1

Niemann-Pick Disease Type C2 (NPC2)

NPC2

Osteochondrodysplasia

TRPV4

Rickets Type I 1, 2

CYP27B1, CYP27B2

Rickets Type IB

CYP2R1

Spasticity (Congenital Myasthenic Syndrome, CMS)

COLQ

Spinal Muscular Atrophy

LIX1

Testicular Hypoplasia and Persistent Primary Dentition

TAC3

For symptoms involving: Blood, Endocrine System, Gastrointestinal Tract, Heart, Immune System, Kidneys, Liver, Reproduction

Number of Alleles Tested: 40

  

Condition

Gene(s)

Acute Intermittent Porphyria (AIP) 1-6

HMBS

Autoimmune Lymphoproliferative Syndrome (ALPS)

FASL

Chediak-Higashi Syndrome

LYST

Congenital Hypothyroidism

TPO

Cystinuria Type IA

SLC3A1

Cystinuria Type IB 1-4

SLC7A9

Cystinuria Type IIB

SLC7A9

Dihydropyrimidinase (DHP)

CPYS

Erythrocyte Pyruvate Kinase Deficiency (PK Deficiency)

PKLR

Erythropoietic Porphyria

UROS

Factor XII Deficiency 1, 2

F12

Glycogen Storage Disease Type IV (GSD IV)

GBE

Hemophilia B 1, 2

F9

Hepatic Copper Accumulation

ATP7B

Hyperlipoproteinaemia

LPL

Hyperoxaluria Type II

GRHPR

Hypertrophic Cardiomyopathy (HCM) 1-3

MYBPC3, MYH7

Leukocyte Adhesion Deficiency Type I

ITGB2

Methemoglobinemia 1, 2

CYB5R3

Mucolipidosis II

GNPTAB

Mucopolysaccharidosis Type I

IDUA

Niemann-Pick Disease Type C1 (NPC1) 1, 2

NPC1

Niemann-Pick Disease Type C2 (NPC2)

NPC2

Polycystic Kidney Disease (PKD)

PKD1

Resistance to FIV 1

APOBEC3C

Testicular Hypoplasia and Persistent Primary Dentition 1

TAC3

Includes all diseases tested in Panels 1-3 and custom sequencing and analysis to identify unique DNA mutations. 

Requires veterinary submission of medical records to guide our scientists in the custom analysis.